Muhammad Sheharyar Ashraf

A distinguished medical professional, specialized in Anesthesia and Critical Care, with an impressive academic and clinical track record. Serving as an Assistant Professor at Lady Reading Hospital in Peshawar, Pakistan, since June 2017, His dedication to improving patient care and advancing medical research has earned him recognition both nationally and internationally.

A graduate of MBBS, with additional qualifications including an MPH, MCPS, FCPS, and CCICM, Dr. Ashraf has built a robust career grounded in clinical excellence and innovative research. His work extends beyond patient care; he is a pivotal member of the Steering Committee for the Pakistan Registry of Intensive Care (PRICE) since 2022 and has been collaborating with PRICE since 2018. Through PRICE, Dr. Ashraf is committed to collecting and analyzing critical data that informs the management of patients in intensive care units across Pakistan.

One of Dr. Ashraf’s most notable roles is as the principal investigator for Mega-ROX Pakistan, a landmark clinical trial embedded within a series of multinational studies aimed at exploring oxygen therapy strategies in critically ill patients. The Mega-ROX study, with a target sample size of 40,000 patients, hypothesizes that a conservative approach to oxygen therapy could reduce mortality compared to a more liberal approach. The trial’s innovative design considers the heterogeneity of treatment response, hypothesizing that patients with acute brain pathologies or sepsis may benefit from more liberal oxygen therapy. This cutting-edge research is poised to challenge existing clinical paradigms and improve outcomes for critically ill patients worldwide.

Dr. Ashraf’s contribution to global health extends to his work on the ISARIC (International Severe Acute Respiratory and Emerging Infections Consortium) COVID-19 Clinical Data Platform. His collaboration with leading institutions such as the Pandemic Sciences Institute and the Nuffield Department of Medicine at the University of Oxford exemplifies his commitment to global health efforts. His exceptional contributions to the ISARIC platform were formally recognized with a Certificate of Appreciation in June 2023, acknowledging his vital role in managing and analyzing COVID-19 data during a global health crisis.

Dr. Muhammad Sheharyar Ashraf’s career reflects not only his expertise in intensive care medicine but also his dedication to research that can shape the future of patient care. His work is a testament to the importance of collaboration, data-driven decision-making, and the relentless pursuit of knowledge in improving healthcare outcomes.